Langerhans' cell histiocytosis (histiocytosis X) of bone a clinicopathologic analysis of 263 pediatric and adult cases

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Langerhans cell histiocytosis

Introduction: Langerhans cell histiocytosis (LCH), which was previously known as histiocytosis X, refers to a group of lesions that stimulate uncontrolled proliferation of cells. The purpose of this case was to report and describe a LCH case with mandibular bone involvement in a 2.5-year-old boy. Case reports: A 2.5 years old boy with LCH of mandibular jaw who has been treated by surgical inter...

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Langerhans cell histiocytosis of bone in children: a clinicopathologic study of 108 cases.

BACKGROUND Langerhans cell histiocytosis (LCH) is a rare disease that is characterized by abnormal proliferation of pathological Langerhans cells (LCs). In this study, a total of 108 pediatric patients with LCH of bone were evaluated retrospectively for illustrating the clinicopathologic features of this disease, with a goal of improving the diagnosis, treatment, and prognosis. METHODS A retr...

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[Adult pulmonary Langerhans cell histiocytosis].

Adult pulmonary Langerhans’ cell histiocytosis is a rare disorder of unknown aetiology that occurs predominantly in young smokers, with an incidence peak at 20–40 yrs of age. In adults, pulmonary involvement with Langerhans’ cell histiocytosis usually occurs as a single-system disease and is characterised by focal Langerhans’ cell granulomas infiltrating and destroying distal bronchioles. High-...

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[Adult pulmonary Langerhans' cell histiocytosis].

INTRODUCTION Adult pulmonary Langerhans'cell histiocytosis, also referred to as histiocytosis X, is a disorder of unknown etiology which affects preferentially young smokers. The disease is characterized by granulomatous lesions which progressively invade and destroy distal airways, leading to the formation of characteristic cicatricial kystic lesions. Florid granulomas contain numerous Langerh...

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Herpes Simplex Virus and Langerhans Cell Histiocytosis

Background and objective: Langerhans cell histiocytosis (LCH) is a rare histiocytic proliferative disorder of unknown etiology and mainly affects young children. The histological feature is granuloma-like proliferation of langerhans-type dendritic cells. Although the possible role of viruses such as Epstein-Barr virus (EBV, Human Herpes virus -4</...

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ژورنال

عنوان ژورنال: Cancer

سال: 1995

ISSN: 0008-543X,1097-0142

DOI: 10.1002/1097-0142(19951215)76:12<2471::aid-cncr2820761211>3.0.co;2-z